An inquiry into the causes and effects of the variolæ vaccinæ, a disease discovered in some of the western counties of England, particulary Gloucestershire, and known by the name of the cow pox
Jenner's 1800 medical inquiry into cowpox, printed in London for the author and sold by booksellers, addressed to physicians and the medical profession. The only picture is the Library of Congress seal, an engraved circle showing a perched eagle above an open book striped like the flag, with stars, a city skyline and a crowd beneath; it is a scan-era institutional emblem rather than an illustration from the book, so a designer might borrow its symmetrical circular seal layout, banded flag stripes and eagle-on-book emblem structure.
